Australian regulator blocks Mafia Casino and other gambling websites iGame

Australian regulator blocks Mafia Casino and other gambling websites

(AsiaGameHub) - Australia's communications regulator has blocked a number of websites operating outside the nation's licensed gambling market, which includes the creatively titled Mafia Casino. A total of 19 online gambling and affiliate websites have been blocked by the Australian Communications and Media Authority (ACMA), as authorities maintain a firm stance against unlicensed operators. The newly blocked sites are: Bass Bet, BetWhale, CasinOK, Cleobetra, Diva Spin, FatPirate, Free Spinz, Gransino, JackBit, Legiano, Mafia Casino, Magius, Monster Win, NewLucky, Nonbetstop.com, Slotexo, Talismania, Tiki Casino and Vegas Hero. The authority commented: "The ACMA is reminding consumers that even if a service appears legitimate, it probably lacks essential customer protections. Australians who use illegal gambling services are therefore at risk of losing their money." Preventing access to a vast number of websites presents a significant challenge for regulators, creating a 'whack-a-mole' situation where operators frequently change their branding to evade detection. Concurrently, the ACMA has issued a formal warning to the sports betting company Chasebet. An investigation found the operator did not sufficiently promote Betstop – Australia's national self-exclusion register – in three marketing emails and on its website. The ACMA reported that Chasebet addressed the problem quickly once notified of the breach, explaining that a software error was to blame. This update on the scale of Australia's black market emerges as the country's politicians debate proposed reforms to gambling advertising regulations. The ACMA stated it has now blocked more than 1,640 illegal gambling websites, with an additional 230 ceasing operations in Australia since enhanced enforcement measures started in 2017. The Labor government, under Prime Minister Anthony Albanese, has put forward plans to limit TV gambling ads to three per hour from 6am to 8.30pm. The proposal also includes a ban on ads during live sports broadcasts and during specified school drop-off and pick-up hours. Furthermore, the government is evaluating a 'triple lock' for digitally distributed gambling content. This would mandate that social media platforms and websites require user logins, age verification for users over 18, and provide an option to opt out of gambling content. However, these digital plans have been criticized as 'unworkable' by opposition MPs, who have raised doubts about the practicality of the triple lock. They point out that adults and children frequently share accounts on services like Spotify and YouTube. Independent MP Kate Chaney stated to The Guardian: "The term 'triple-lock' implies a level of protection that is not realistic – since most families share streaming accounts, gambling ads will still be seen unless parents meticulously navigate each platform to find and enable the opt-out settings." A spokesperson for Communications Minister Anika Wells has verified that 'specific definitions' will be published to prevent loopholes before the new laws are implemented. iGaming Expert analysis: Although gambling reform in Australia has been intensely debated since the 2023 Murphy Report, political disagreement risks weakening the legal market and strengthening illegal operators. For the regulated sector to remain healthy, the Labor Government must find a balanced solution that enhances consumer protection while also supporting the growth of licensed businesses. This article is provided by a third-party. AsiaGameHub (https://asiagamehub.com/) makes no warranties regarding its content. AsiaGameHub delivers targeted distribution for iGaming, Casino, and eSports, connecting 3,000+ premium Asian media outlets and 80,000+ specialized influencers across ASEAN.
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EU Ruling Presents Malta with New Setback to Foreign Challenges of iGaming Licenses iGame

EU Ruling Presents Malta with New Setback to Foreign Challenges of iGaming Licenses

(AsiaGameHub) - Concerns that a flood of players might seek to recover losses from Maltese operators have grown stronger following the latest ruling by the Court of Justice of the European Union (CJEU). The CJEU has sided with the view that contracts between players residing in Germany and operators without a license in the country are fundamentally void. Prolonged legal disputes between Malta and the EU member states of Germany and Austria over numerous compensation claims have escalated over the past decade, requiring a determination from the Attorney General of the CJEU. In a preliminary ruling requested by Malta’s First Hall of the Civic Court, the EU court outlined that players may be entitled to claim back losses from operators not licensed in the country. The European Court held that Article 56 TFEU – an EU law governing restrictions on the provision of unrestricted services – does not take precedence over national laws related to online gambling disputes. The latest ruling will be a setback for Malta’s legislative framework, as it continues to face cases against operators regarding compensation for former customers of unlicensed entities. At the time the relevant activities took place in Germany, the country’s regulatory frameworks had not yet been finalized by the Bundestag, Germany’s federal government. Since then, the framework has shifted due to the Glücksspielneuregulierungsstaatsvertrag (GlüNeuRStV), the online gambling regulatory framework launched in July 2021. However, the EU’s preliminary ruling stated that a change in German lawmakers’ approach to the gambling sector did not invalidate the prior prohibition in place when the wagers were made. That said, the CJEU’s ruling is somewhat unsurprising and continues the trend away from Malta, given a previous opinion by Advocate General (AG) Nicholas Emiliou of Cyprus, which noted: “A sports betting operator that offers services in a national market without the required license may be required to refund the stakes collected from players.” This was in relation to a long-running German dispute challenging Tipico Malta’s online gambling license over loss recovery for the period between 2013 and 2020. Malta has yet to enact Bill 55 in the specific case ruled on by the CJEU, which involved Lottoland and two German players. Even so, Malta could still rely on the law as a shield against EU regulations and domestic frameworks in EU markets. Whether this will provide an effective shield for Maltese operators remains to be seen, however, given key developments from the latest EU ruling stating that Article 56A of the TFEU “must be interpreted as not precluding national legislation which imposes a prohibition on the organization of online casino games, in particular slot machines, and of forms of betting such as online betting on the results of lottery draws.” Germany’s regulator, the GGL, has been one of the most vocal critics of Maltese operators being shielded from European law. The GGL has pursued the case with the European Commission, arguing that the bill needs to be reassessed, along with its alignment with EU frameworks. Previously, the GGL stated: “We are of the opinion that this law should not be compatible with European requirements for the recognition of decisions (Regulation (EU) 1215/2002). “However, the final assessment of this question is not the responsibility of the GGL. We have informed the federal states of our assessment and are otherwise in contact with the relevant authorities.” This article is provided by a third-party. AsiaGameHub (https://asiagamehub.com/) makes no warranties regarding its content. AsiaGameHub delivers targeted distribution for iGaming, Casino, and eSports, connecting 3,000+ premium Asian media outlets and 80,000+ specialized influencers across ASEAN.
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EGBA calls proposed EU online gambling levy fundamentally unworkable iGame

EGBA calls proposed EU online gambling levy fundamentally unworkable

(AsiaGameHub) - The European Gaming and Betting Association (EGBA) has criticized a proposed EU online gambling levy that would be imposed alongside existing national gambling taxes, labeling the initiative as ‘fundamentally unworkable’. According to the EGBA, an EU online gambling levy would solely favor unlicensed operators, coming at the ‘cost of consumer protection’ and cutting into member states’ tax incomes. The European Parliament’s Budget Committee approved the EU’s upcoming long-term budget—the Multiannual Financial Framework (MFF) for 2028-2034—by a vote of 26 to 9 (with five abstentions). This framework references possible new direct revenue sources, such as an EU online gambling levy. While the framework moves forward to the next phase, EGBA Secretary General Maarten Haijer is urging lawmakers to rethink the levy due to its possible effects on the sector. Haijer stated: “Today’s vote is a provisional, conditional request for Member States to look into the concept of an EU online gambling levy. It is not a formal proposal or a final decision. At present, gambling is not standardized across the EU, and there is no legal foundation to outline, manage, or collect this type of levy. “Putting these legal barriers aside, adding another levy on top of existing national taxes—especially in a sector where licensed operators in certain Member States already face tax rates over 50% of their gross gaming revenue—would leave only one group better off: unlicensed operators.” Maarten Haijer, Secretary General of the European Gaming and Betting Association. Image: SBC Media Victor Negrescu, Vice President of the European Parliament, put forward a unified levy on European online gambling and betting services during a plenary session in February, noting it could bring in an extra “€2bn to €4bn annually”. For the levy to become a new direct revenue source for the EU budget, all 27 member states must agree unanimously via the EU Council. The European Parliament is set to vote on the Committee’s stance at its late April plenary session. Following that, formal MFF negotiations will start, with a resolution anticipated by the end of 2026. Haijer added: “Since they don’t pay taxes, unlicensed operators can already offer players more appealing products and prices, without any of the consumer protections that licensed operators have in place. “Introducing an EU levy would exacerbate this issue: it would grow the black market, undermine consumer protection for EU residents, and lower total tax revenues for Member States.” Interested in more stories like this? Visit the new SBC Media YouTube Channel—SBC’s new hub for all multimedia content—where our team takes an in-depth look at the top stories from the sports betting, iGaming, affiliate, and payments sectors. This article is provided by a third-party. AsiaGameHub (https://asiagamehub.com/) makes no warranties regarding its content. AsiaGameHub delivers targeted distribution for iGaming, Casino, and eSports, connecting 3,000+ premium Asian media outlets and 80,000+ specialized influencers across ASEAN.
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Entain keen to embrace new UK opportunities iGame

Entain keen to embrace new UK opportunities

(AsiaGameHub) - Entain has highlighted its strong interest in the UK gambling sector, as Chief Executive Officer Stella David noted that the operator is expanding its market presence as the 40% remote gaming duty (RGD) period commences. Mike Snape, Chief Financial Officer, pointed out that the UK gambling industry has been compelled to evolve due to tax reforms, which David described as ‘draconian’, thereby creating openings for Entain to secure market share. During this accelerated market transformation, Snape revealed that the operator has refused to slow down, whereas many other market participants have seen their enthusiasm dampened by such harsh tax adjustments. “We are capitalizing on the current market landscape, and this represents just the beginning of what we believe we can accomplish with our UK operations.” David also offered a positive outlook on Entain’s performance in the UK. She informed investors that the company aims for further market share expansion, reporting a 6% year-over-year rise in UK & Ireland net gaming revenue (NGR), with online NGR climbing 13%. When asked about the impact of the UK’s RGD rise, David remarked: “It’s really too early to say. I think the more important point is that we have definitely been increasing our share in the UK in advance of those tax increases and part of our strategy is to continue to increase our share. “Certainly in gaming, if you look at the market, there is a long tail of tier two and tier three operators all having very small percentage shares of the market, so within the regulated sector, we definitely see there’s an opportunity to continue to build on that share gain. We will see over time just how much of an impact that the black market has on the overall growth of the regulated sector.” Despite the changing market, David encouraged the industry to persist in lobbying the government. She stated it is vital to prevent further encroachment by the black market resulting from stricter regulations. The World Cup has been consistently identified as a major opportunity for Entain to gain market share. However, David revealed the operator is approaching the event with realistic expectations. David detailed that the tournament will be ‘a rollercoaster’, emphasizing that during its early stages, margins are tight with lopsided games. She added that the focus is more on recruitment. NGR growth amidst retail battles Entain’s group NGR grew by 3% YoY in Q1, with gaming NGR up 7% YoY but sports NGR down 3% YoY. Online NGR improved by 5% YoY, while retail NGR decreased by 3% YoY. International NGR increased by 1% YoY, with online NGR up 2% YoY, but retail NGR fell by 4% YoY. CEE NGR dropped by 6% YoY, with online and retail NGR declining by 1% and 30% YoY, respectively. BetMGM revenue reached $696m, up 6% YoY. Total group NGR, including BetMGM, rose by 5% YoY. Entain also confirmed its 2026 guidance, projecting 5%-7% online NGR growth on a constant currency basis, remaining confident in market expectations for group underlying EBITDA, as well as achieving at least £500m of annual adjusted cashflow in 2028. This article is provided by a third-party. AsiaGameHub (https://asiagamehub.com/) makes no warranties regarding its content. AsiaGameHub delivers targeted distribution for iGaming, Casino, and eSports, connecting 3,000+ premium Asian media outlets and 80,000+ specialized influencers across ASEAN.
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穆迪(Moody’s)執行長:人工智慧存在信任問題——更好的模型無法解決它

(SeaPRwire) - 幾乎每週,關於人工智慧的新聞頭條都被最新模型的消息所主導。幾天前,Meta宣布了其名為Muse Spark的最新模型——這是其改組後AI部門推出的首個模型。根據其內部基準測試,新模型在多項任務上與領先競爭對手相比具有競爭力。 然而,每一次新模型的發布都揭示了一個違反直覺的現象:湧入市場的模型越多,它們就越成為商品。如果是這樣,那麼問題就變成了:對於試圖採用和擴展AI的企業來說,差異化因素是什麼? 答案歸結為一個詞——信任。 隨著時間推移,放在你桌上的模型將不如輸入其中的、可信賴的、相互連結的智慧來得重要。我將「連結的智慧」視為從多個有組織的來源提取並經過策展的數據。因此,AI模型可以同時對所有數據進行推理,而不是基於單一、不完整的圖像進行工作。 另一種思考方式是:AI模型是我們每天駕駛且不斷改進的汽車。然而,數據和智慧是導航系統——它區分了「知道自己在移動」和「知道要去哪裡」。一個運行在過時地圖上的基本GPS或許能帶你到某個地方——但它能可靠且快速地帶你到達目的地嗎? 也許。 但當涉及高風險決策時——尤其是在金融服務領域——「也許」是不夠的。我們談論的是世界上一些影響深遠的決策,這些決策影響人們獲得貸款、獲得負擔得起的保險以及保護資金免受金融犯罪侵害的能力。這些模型需要一個可靠的「真相來源」來進行推理——否則,我們不僅增加了不良結果的可能性,更是在公眾對機構的信任度全球性下降之際,拿公眾信任進行賭博。 NVIDIA執行長黃仁勳最近闡明了這一點,他說:「結構化數據是人工智慧的基礎真相。」他指出了業界一直遲遲未承認的事實:強大的模型需要可信的數據。而並非所有數據都能贏得這種區別。 數據需要被組織、標準化,並根據世界的實際運作方式進行校準。這是一項艱鉅的工作,無法僅透過網路爬取來完成,這就是為什麼將最佳模型與這種連結智慧相結合的組織將建立信任。此外,這也將確保基於AI的決策能夠向董事會、監管機構、客戶和股東證明其合理性。 數據基礎出錯的後果已經顯現。根據MIT的數據,95%的AI試點項目未能產生可衡量的影響。部分原因在於數據基礎過於薄弱。更強大的模型並不能解決這個問題——如果說有什麼影響,那就是它們使得產生不良輸出的後果更難被檢測,且逆轉成本更高。 閱讀新聞,不良輸出的風險顯而易見:關稅正在一夜之間重塑全球貿易,地緣政治正在重繪供應鏈,極端天氣事件正在挑戰歷史模型,網路攻擊正在針對關鍵基礎設施。正如世界經濟論壇的《2026年全球風險報告》所明確指出的,風險的規模、互聯性和速度持續螺旋式上升。 對於銀行、保險公司和資產管理公司而言,這種互聯性並非理論上的——它區分了「對風險做出反應」和「領先於風險」。在這個「指數級風險」時代,決定性的挑戰不僅在於威脅的規模在增長——它們的互聯性也在增強。例如,一個損壞基礎設施的極端天氣事件可能會影響關鍵的供應鏈節點,從而對經濟增長和信貸產生衍生影響。對於金融服務公司來說,使用通用AI加上碎片化的數據,無法就如何評估這些風險得出一個站得住腳的答案。然而,連結的智慧——涵蓋氣候、信貸和合規等不同數據集——可以讓你更接近一個你能信任的答案。 隨著更多數據源的統一,一幅比任何孤島式方法所能產生的都更全面、更精確、更具可操作性的風險圖景便會浮現。這就是為什麼那些將第三方數據與自有數據相結合的公司,將能夠做出更好、更快的決策——並能在關鍵時刻為這些決策辯護。 在過去三年中,模型的複雜性和能力已大幅提升。然而,現在是時候開始專注於完善其背後的智慧了。這些決策並非僅為工程師保留。它們適用於任何認真想要釋放AI真正潛力的人。每個大規模部署AI的組織都需要向其數據團隊提出與詢問AI供應商相同的問題:這種智慧是否可靠、相互連結,並經過真實結果的測試? 因為這不僅關乎收入和成長,對於任何關心強化市場所依賴的制度性信任的人來說,這同樣重要。Moody's在一個多世紀前成立,其信念是:當每個人都能獲得透明、嚴謹且獨立的數據與分析時,市場運作會更好。這一原則在今天與當時一樣正確,AI並未改變這一原則——它只是提高了犯錯的成本。本文由第三方廠商內容提供者提供。SeaPRwire (https://www.seaprwire.com/)對此不作任何保證或陳述。 分類: 頭條新聞,日常新聞 SeaPRwire為公司和機構提供全球新聞稿發佈,覆蓋超過6,500個媒體庫、86,000名編輯和記者,以及350萬以上終端桌面和手機App。SeaPRwire支持英、日、德、韓、法、俄、印尼、馬來、越南、中文等多種語言新聞稿發佈。
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Turkey intensifies crackdown on illegal gambling by targeting digital platforms iGame

Turkey intensifies crackdown on illegal gambling by targeting digital platforms

(AsiaGameHub) - Media companies operating in Turkey have received a warning that more stringent checks of content and platforms will be carried out to prevent the promotion of illegal gambling services. This direct warning comes from Ticaret Bakanlığı, Turkey’s Ministry of Trade, following the department’s completion of its latest advertising sweep of digital platforms. Drawing mainstream media attention in Turkey, the Ministry announced that it had “blocked 15 high-follower social media accounts,” though it has yet to disclose the identities of the individuals involved and which platforms they were misusing. Turkish media outlets were informed that the “individuals will be charged for promoting illegal gambling platforms with access to all their online inventory blocked.” This enforcement action forms part of a broader crackdown led by the Ministry’s Advertising Board, which has concluded an ‘investigation of 132 cases, finding 117 in breach of national advertising rules’. The board has issued administrative fines totalling TRY 49.8m (€1m), underscoring the Ministry of Trade’s intent to tighten oversight of advertising on digital platforms. The Ministry has reported to the federal government that it views social media and, in particular, influencer-led content as a ‘priority concern’ regarding how Turkish audiences are being exposed to illegal gambling websites. Digital platforms have been warned that they must guarantee the safety of their media environments, ensuring shared responsibility for compliance with advertising standards. Expanding sanction limits As such, enforcement will not be limited to account suspensions; additional financial penalties and potential legal proceedings are on the table for repeat offenders. Both foreign and domestic media incumbents were advised to strengthen internal controls and vet third-party advertising partners more rigorously to avoid exposure. Turkey’s crackdown on illegal gambling is being formalized into a fully centralized enforcement model, with Ticaret Bakanlığı now expected to report directly to Justice Minister Akın Gürlek on the monitoring of online platforms, advertising activity, and digital environments. The move signals a tightening alignment between commercial regulators and criminal enforcement bodies, as Ankara expands scrutiny of how illicit operators use media channels to reach Turkish consumers. Gürlek’s appointment in March, replacing Yılmaz Tunç following a reshuffle ordered by President Recep Tayyip Erdoğan, sets a new tone for enforcement. Tasked with prioritizing the prosecution of unlicensed gambling platforms, the former Istanbul Chief Prosecutor has moved quickly to impose a coordinated, nationwide framework. In his first month in office, Gürlek issued directives to 171 Public Prosecutors’ Offices across all 81 provinces, requiring structured cooperation with police and financial intelligence units. The scale of enforcement is already being felt. Gürlek confirmed that authorities conducted 729 operations in March targeting drug offences, illegal betting, and online gambling, resulting in 2,996 arrests and judicial measures against a further 820 suspects. These actions underline the government’s shift from regulatory oversight to active disruption and prosecution of illicit networks. At the centre of this effort sits the intelligence agency MASAK, which continues to act as the financial gatekeeper by monitoring suspicious transactions and feeding intelligence into criminal cases. Prosecutors have been instructed to strengthen evidence collection, particularly in digital environments, with a focus on asset tracing and the identification of operators targeting local communities. The next phase of enforcement will be shaped by Turkey’s 11th Judicial Package, due to take effect in 2026. The reforms introduce harsher prison sentences, higher financial penalties, and the direct seizure of accounts linked to illegal gambling activity. Industry observers are now watching closely to see whether breaches tied to media and advertising will also fall under the expanded scope of these measures. Taken together, the developments point to a more aggressive and coordinated strategy—one that places media platforms, financial systems, and law enforcement under a single enforcement umbrella. For operators and their affiliates, the message from the President and central government is unambiguous: the space to promote or facilitate illegal gambling in Turkey is rapidly tightening across finance, media, and digital landscapes. This article is provided by a third-party. AsiaGameHub (https://asiagamehub.com/) makes no warranties regarding its content. AsiaGameHub delivers targeted distribution for iGaming, Casino, and eSports, connecting 3,000+ premium Asian media outlets and 80,000+ specialized influencers across ASEAN.
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Tamazi Gambashidze: the key factor behind the growth of World Cup BetBuilder iGame

Tamazi Gambashidze: the key factor behind the growth of World Cup BetBuilder

(AsiaGameHub) - Looking ahead at how BetBuilders will evolve ahead of the World Cup, Tamazi Gambashidze, Head of the Sports Brand Experience Department at Adjarabet, shared two key factors that can help bring the product to new audiences. Gambashidze also noted his view that slightly raising margins for BetBuilders makes sense, during his conversation with iGaming Expert about sportsbook products during this summer’s major sporting event. iGaming Expert: Could you elaborate on how you think bet builders will change over the coming years? Tamazi Gambashidze: Artificial intelligence and personalization will further advance BetBuilders. The more data we incorporate, the more efficient the tool will become, as every user will receive tailored suggestions based on their past betting activity. A wider range of sports and betting markets will be added. In my part of the world, BetBuilders are still a relatively new feature, so not many users have tried them yet, but by the end of the 2020s, roughly half of all bettors could be placing wagers via BetBuilder. I’d also love to see BetBuilders expand into in-play betting, as from our experience, most users currently place pre-match bets, but adding this functionality would ultimately boost user engagement. iGaming Expert: Is it a given that operators must raise margins on BetBuilders to keep them appealing to users? Tamazi Gambashidze: Slightly raising margins makes sense, given the high level of competition in the BetBuilder space. The correlations between different betting markets are stronger, and the underlying logic hinges on whether one event or action occurs, which makes the likelihood of a linked action happening far greater. Users only see straightforward odds, and from our experience, they don’t understand why BetBuilder odds are lower than those for individual standalone markets. To avoid this negative user response, bookmakers will most often adjust margins for BetBuilder wagers. iGaming Expert: How significant a platform will the World Cup be for BetBuilders and sportsbook user engagement? Tamazi Gambashidze: The World Cup is the marquee event that every online gambling operator has been anticipating, with promotions like free-to-play games and tournament brackets driving activity. A huge number of products are being tailored for the World Cup, as it offers an ideal chance to trial new features and concepts. The majority of betting markets can’t be combined in a single betslip, and matches are mostly treated as separate entities (apart from the final matchday of the group stage), so BetBuilders are the perfect option for users who enjoy multi-wager bets, letting them take part in single-game multi bets. iGaming Expert: What kind of impact will second-screen engagement have on European football fans during the World Cup? Tamazi Gambashidze: Game kickoff times are really inconvenient for European fans. Picture having to place bets at 2 a.m., 4 a.m., or 5 a.m. — that would be a total nightmare. But given the scale of this tournament, I think in-play betting will still remain popular. Second-screen engagement will help drive interest in some new football betting markets, and micro-betting, which is far less common in Europe than it is in the United States, is set to gain traction during the World Cup thanks to this type of engagement. iGaming Expert: What will the key drivers be for cross-selling sportsbook users to casino products during the World Cup? Tamazi Gambashidze: The World Cup is a one-of-a-kind opportunity for cross-selling. I recall during Euro 2024, when my home country Georgia competed for the first time, we saw a massive jump in users who engaged with multiple of our products. There is a clear divide between countries that are competing in the World Cup and those that are not. For this tournament’s debutant teams: Cape Verde, Curaçao, Jordan, and Uzbekistan. Online betting is legal in three of these nations, so this will be a massive opportunity for operators in those three countries to cross-sell sportsbook users and attract customers to their other product lines. iGaming Expert: Are there any key steps operators can take to keep users engaged after their first bet of the tournament? Tamazi Gambashidze: The most critical factor is to make the sportsbook as user-friendly as possible. For regular sportsbook users, things can stay largely the same, but for new users, they prefer a sportsbook that is as simple and straightforward as possible. Another major piece of the puzzle is to keep users active from the first day of the tournament right through to the final match. If you can pull that off, you’ll turn them into loyal, long-term customers. This article is provided by a third-party. AsiaGameHub (https://asiagamehub.com/) makes no warranties regarding its content. AsiaGameHub delivers targeted distribution for iGaming, Casino, and eSports, connecting 3,000+ premium Asian media outlets and 80,000+ specialized influencers across ASEAN.
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The gaming sector in the UAE attains a new milestone iGame

The gaming sector in the UAE attains a new milestone

(AsiaGameHub) - The United Arab Emirates lottery has expanded into the physical realm with the launch of its inaugural land-based location, where customers can now buy tickets for lottery draws. Initially launched in December 2024, the UAE Lottery was accessible solely via digital platforms. The debut of a brick-and-mortar store in Musaffah, Abu Dhabi, now enables players aged 18 and above to buy tickets directly for games like Lucky Day Draw and Pick 3. As reported by Gulf News, the UAE Lottery stated: “Every aspect, from striking visuals to user-friendly layouts, has been designed to create a seamless and captivating customer experience. Prominent signage and an inviting, open interior encourage steady visitor traffic, and interactive displays alongside attentive staff guarantee that every visit is both educational and pleasurable.” The organization also reaffirmed its dedication to responsible gambling, noting that customer service personnel will be on hand to support players. All games will be overseen by the national regulator, the General Commercial Gaming Regulatory Authority. “The UAE Lottery offers a variety of tools and materials to empower participants to make educated decisions, fostering a secure, enjoyable, and equitable lottery setting.” We’re officially open. Our very first retail shop is here!Walk in, say hi, and let our team give you the warmest welcome. Grab your tickets in person and experience the lottery like never before! M40, Musaffah, Abu Dhabi: https://t.co/iFkbx7G8NZ Open Daily, 9:00 AM –… pic.twitter.com/zSryXqdY57— The UAE Lottery (@theuaelottery) April 15, 2026 This move to establish a physical lottery outlet in the UAE coincides with ongoing developments by multiple casino companies, which are constructing their own venues for gaming operations. MGM Resorts International CEO, Bill Hornbuckle, recently noted that the company is optimistic about the prospects of its non-gaming management deal. This agreement could introduce its Bellagio, Aria and MGM Grand brands to the area in partnership with Wasl Hospitality in Dubai, a location that may eventually host a casino. Hornbuckle remarked: “It’s not our project, so the construction and funding are handled by Wasl. However, it establishes a foundation for a potential casino in the future. “In the long run, we are particularly enthusiastic about the airport's location and its development trajectory. We believe Dubai is the key market. For the present, we are content with a management agreement to operate what we view as a genuine brand extension, and we shall observe how things progress.” Concurrently, Wynn Resorts is developing the nation's first licensed casino resort, Wynn Al Marjan Island, in Ras Al Khaimah. Construction has recommenced following a temporary halt caused by regional conflict. Interested in more stories like this one? Visit the new SBC Media YouTube Channel, the central hub for all multimedia content at SBC, where our experts provide in-depth analysis of the major news from the sports betting, iGaming, affiliate, and payments sectors. This article is provided by a third-party. AsiaGameHub (https://asiagamehub.com/) makes no warranties regarding its content. AsiaGameHub delivers targeted distribution for iGaming, Casino, and eSports, connecting 3,000+ premium Asian media outlets and 80,000+ specialized influencers across ASEAN.
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US imposes sanctions on Mexican casinos due to cartel connections iGame

US imposes sanctions on Mexican casinos due to cartel connections

(AsiaGameHub) - Authorities in the United States have imposed sanctions on two Mexican casinos due to their connections with the Cartel del Noreste, an organization previously labeled a terrorist group by the Trump administration. The Office of Foreign Assets Control (OFAC) of the US Department of the Treasury has asserted that the Casino Centenario in Nuevo Laredo serves as a ‘stash house’ for drugs and a conduit for laundering illegal money for the cartel. Additionally, OFAC has sanctioned the Diamante Casino and Comercializadora y Arrendadora de Mexico, S.A. de C.V., the corporation responsible for operating both establishments. Scott Bessent, the Secretary of the Treasury, stated: “As President Trump has articulated, the Treasury will deploy every available instrument to safeguard our nation from violent cartels seeking to inflict terror upon innocent Americans. “The Treasury remains committed to targeting the various income sources that cartels depend on to maintain their activities, such as the trafficking of fentanyl and undocumented immigrants into the United States.” OFAC characterized the Cartel del Noreste as one of ‘Mexico’s most brutal drug trafficking organizations,’ headquartered in Nuevo Laredo, a bustling commercial port situated on the US-Mexico frontier. This group emerged from the Los Zetas organization in 2014 and faces accusations of involvement in drug smuggling, human trafficking, money laundering, and extortion. In addition to these businesses, Eduardo Javier Islas Valdez has also been sanctioned, facing allegations of overseeing the organization’s human smuggling activities. Concurrently, OFAC alleges that attorney Juan Pablo Penilla Rodriguez is rendering unlawful services to the cartel, and activist Jesus Reymundo Ramos Vazquez is submitting fraudulent claims against Mexican authorities to disseminate cartel disinformation. These sanctions freeze assets held by the designated individuals and entities within the US and forbid individuals from conducting business with them in the United States. OFAC had previously sanctioned five senior members of the group, and this latest measure further emphasizes OFAC’s scrutiny of casino establishments throughout Mexico, which are suspected of being utilized by some of Mexico’s most prominent criminal organizations to launder illicit gains. Last November, the US imposed sanctions on members of the Sinaloa Cartel-linked Hysa Organized Crime Group, as well as Entretenimiento Palmero, S.A. de C.V. – a casino and entertainment firm owned by one of its members. In total, the Financial Crimes Enforcement Network issued notices to ten casinos connected to the group. This article is provided by a third-party. AsiaGameHub (https://asiagamehub.com/) makes no warranties regarding its content. AsiaGameHub delivers targeted distribution for iGaming, Casino, and eSports, connecting 3,000+ premium Asian media outlets and 80,000+ specialized influencers across ASEAN.
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Bybit Co-Founder Observes Trust and AI Redefining Financial Infrastructure iGame

Bybit Co-Founder Observes Trust and AI Redefining Financial Infrastructure

(AsiaGameHub) - The financial industry is moving toward a more subtle evolution. During Paris Blockchain Week 2026, Bybit co-founder and CEO Ben Zhou remarked that the upcoming stage will focus on AI agents, stablecoins, and transparent oversight rather than market speculation. Key Highlights Ben Zhou suggested that users might soon delegate market operations and transactions to AI agents. He identified stablecoins as a functional link between traditional finance and blockchain technology. He also noted that institutional participation is growing due to more defined regulations in regions like the UAE. Ben Zhou Outlines a Financial Future That Operates Seamlessly in the Background During a fireside chat at Paris Blockchain Week 2026, Ben Zhou shifted the dialogue from price volatility to the importance of infrastructure. Speaking with BeInCrypto’s Brian McGleenon on April 15, he envisioned a financial landscape defined by AI, asset tokenization, and increasingly clear regulatory frameworks. A central component of this vision is what Zhou termed agentic finance. Bybit has already debuted AI agent accounts, which permit clients to set up sub-accounts where AI systems can interact, carry out strategies, and retrieve market data. He noted: “We have introduced AI agent accounts that enable users to create sub-accounts for AI to engage, execute various strategies, and pull market information. The rise of agentic payments is a major developing trend — and this is only the beginning.”His core argument was that users may no longer need to manage every individual step of a transaction. Instead, AI agents could interpret data and manage execution instantly. In such a framework, the specific platform becomes less critical as the intelligence layer takes on more responsibility. Zhou further contended that the primary story is not about speculation. He believes traditional finance is already utilizing blockchain for functional purposes like settlement, payments, and liquidity access. Stablecoins are at the heart of this transition. According to Zhou, many institutions are adopting this infrastructure while often avoiding the "crypto" label entirely. This shift makes established trust more vital than mere innovation. Zhou observed that regulation is now acting as a catalyst rather than a barrier. “The regulatory landscape has seen significant clarification lately. Jurisdictions such as the UAE are at the forefront, actively supporting innovation and providing clear roadmaps for development.”He also mentioned the UK, US, and Europe as regions where policy clarity is helping the market reach maturity. As these rules become more established, larger institutional players are becoming more confident about entering the industry. Zhou concluded by emphasizing that the goal is to refine existing financial processes rather than replace them. “This isn't about substituting current financial frameworks, but rather making them better. Our priority is creating infrastructure that ensures financial services are more intuitive, efficient, and accessible to a global audience.” His ultimate vision is a world where users rarely have to think about wallets, platforms, or blockchain technology. The service simply operates. Trust is embedded within the system, intelligence functions behind the scenes, and the underlying technology becomes virtually invisible. This article is provided by a third-party. AsiaGameHub (https://asiagamehub.com/) makes no warranties regarding its content. AsiaGameHub delivers targeted distribution for iGaming, Casino, and eSports, connecting 3,000+ premium Asian media outlets and 80,000+ specialized influencers across ASEAN.
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Rising Oil Costs Squeeze Gaming Industry, Warns Pagcor’s Alejandro Tengco iGame

Rising Oil Costs Squeeze Gaming Industry, Warns Pagcor’s Alejandro Tengco

(AsiaGameHub) - The gaming industry is facing increased pressure due to rising energy expenses. Alejandro Tengco, head of Pagcor, observed that markets in Asia and the United States are already experiencing the effects, with the Philippines also grappling with higher domestic fuel prices. Good to Know Pagcor indicated that the global gaming sector is being impacted by the oil crisis. Alejandro Tengco identified the US, Macau, and Singapore as affected regions. A decision is still pending regarding the proposal to separate Pagcor's operating and regulatory responsibilities. Tengco Notes Global Gaming Impact from Oil Crisis Alejandro Tengco stated that the international gaming industry is under strain from an oil crisis linked to Middle Eastern conflicts. During an industry gathering in Manila organized by Inside Asian Gaming, the Pagcor chairman and CEO noted that regions including Macau, Singapore, and the US are all feeling the repercussions. Approximately one-fifth of the world's oil and gas comes from the Gulf. Since military actions involving the US, Israel, and Iran began on February 28, energy supplies and maritime commerce have faced disruptions. This is significant for the Philippines, which depends heavily on Middle Eastern fossil fuel imports, leading government agencies to implement energy-conservation measures. Fuel costs have surged, with gasoline and diesel prices in the Philippines more than doubling since the start of the conflict. The national government recently announced the suspension of certain fuel taxes to help consumers. Furthermore, analysts have pointed out the increasing pressure on Macau's gaming industry as energy expenses rise.In a Wednesday statement following the event, Pagcor quoted Tengco: “This is a difficult period for everyone.” He also advocated for stronger industry cooperation amidst shifting conditions. “It is vital that we unite, maintain these dialogues, and provide mutual support within the sector,” Mr. Tengco remarked. He added that Pagcor would adapt as necessary while prioritizing player safety. He stated: “Pagcor will make the required adjustments. We must stay current and ensure that our focus remains on responsible gaming.”The session also revisited the long-standing debate over Pagcor's organizational structure. Tengco confirmed that the Governance Commission for Government Owned and Controlled Corporations (GCG) continues to evaluate the plan to decouple Pagcor's commercial and regulatory arms. This strategy involves Pagcor retaining its regulatory role while privatizing the state-run Casino Filipino chain. Tengco commented: “There is significant demand for this separation, and we are awaiting the GCG's verdict,” he said. “Should privatization be approved, it will represent a major shift for the industry.” This article is provided by a third-party. AsiaGameHub (https://asiagamehub.com/) makes no warranties regarding its content. AsiaGameHub delivers targeted distribution for iGaming, Casino, and eSports, connecting 3,000+ premium Asian media outlets and 80,000+ specialized influencers across ASEAN.
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Kentucky Lawmakers Lift Veto and Raise the Betting Age to 21 iGame

Kentucky Lawmakers Lift Veto and Raise the Betting Age to 21

(AsiaGameHub) - Kentucky has enacted new sports betting regulations following a veto override by state legislators against Gov. Andy Beshear. The legislation increases the minimum age for betting and imposes restrictions on prediction markets. Good to Know Kentucky will raise the sports betting age from 18 to 21 in 90 days. HB 904 also blocks sportsbook ties to prediction markets such as Kalshi and Polymarket. Player props on in state college teams will no longer be allowed. Kentucky Overrides Veto and Reshapes Betting Rules By overriding a veto from Gov. Andy Beshear, Kentucky legislators enacted HB 904 into law, which increases the legal sports betting age from 18 to 21. This new age requirement will take effect in 90 days for all nine online sportsbooks and physical betting locations statewide. The minimum age for betting on horse races remains 18. The General Assembly initially approved the bill earlier this month and revisited it after Beshear vetoed it on Monday. The House voted 67 to 7 to override the veto, and the Senate did the same on Tuesday just before the legislative session concluded. Beshear's primary objection to the bill was a provision that allows Kentucky's gaming and horse racing regulators to enact emergency and standard administrative regulations without requiring the governor's review or signature.The scope of the new law extends beyond the age increase. It also prohibits operators of sports betting, fantasy sports, and horse racing from providing prediction markets or forming partnerships with trading platforms like Kalshi or Polymarket. While DraftKings, FanDuel, and Fanatics all operate sportsbooks in Kentucky and introduced prediction market platforms in late 2025, none of these companies currently offer such markets in states where their sportsbooks are active. Additionally, HB 904 prohibits player proposition bets on teams from colleges within the state, covering wagers on individual performances like points scored or touchdowns. Daily fantasy sports operators like Underdog and PrizePicks will now be required to obtain a license to offer contests in Kentucky. For horse racing, operators are now permitted to offer fixed odds betting in addition to traditional pari-mutuel wagering. This article is provided by a third-party. AsiaGameHub (https://asiagamehub.com/) makes no warranties regarding its content. AsiaGameHub delivers targeted distribution for iGaming, Casino, and eSports, connecting 3,000+ premium Asian media outlets and 80,000+ specialized influencers across ASEAN.
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Alberta Joins Supreme Court Battle Over Canada’s iGaming Outlook iGame

Alberta Joins Supreme Court Battle Over Canada’s iGaming Outlook

(AsiaGameHub) - Canada's top court will hear from Alberta in a gambling case that could impact online sports betting, poker, paid DFS, and casino gaming nationwide. The outcome is also significant for Alberta's own iGaming launch scheduled for July 13. Good to Know Alberta is permitted to submit a 10-page factum and present a five-minute oral argument. The case has the potential to influence poker liquidity, paid DFS, online casino gaming, and sports betting across Canada. Alberta believes the appeal could shape the operational framework of the iGaming Alberta Act. Alberta Secures Role in Case That Could Reshape Canada's iGaming Market Alberta has gained a position in a pivotal gambling case before the Supreme Court of Canada. On Monday, the court granted the Attorney General of Alberta permission to intervene, allowing the province to submit a factum of up to 10 pages and deliver a five-minute oral argument during the upcoming hearing. This access is subject to certain limitations. Alberta is not allowed to argue for a specific outcome of the appeal, introduce new issues, present additional evidence, or reiterate arguments already made by other parties. The court's decision states:“The intervener is not entitled to express a position on the disposition of the appeal, to raise new issues, to adduce further evidence or otherwise to supplement the record of the parties.” It further clarifies: “The intervener is not permitted to advance submissions that duplicate those of the other parties.” Despite these restrictions, Alberta will now have a voice in a case that could significantly alter the landscape of online sports betting, internet casino gaming, daily fantasy sports, and poker operations in Canada. This is particularly relevant as Alberta is preparing to launch a competitive iGaming market on July 13. Under a new provincial framework, private operators are expected to enter the market alongside Play Alberta, the province's sole regulated operator currently. Major brands such as bet365, DraftKings, and FanDuel are reportedly preparing for this launch. Why the Ontario Dispute is Relevant to Alberta The current case originated from Ontario, which launched its private sector iGaming market in April 2022. Ontario's regulations classify pay-to-play DFS contests as gambling and mandate that all wagers must be placed from within the province. This has limited the potential for online poker pools and effectively excluded paid DFS from Ontario. Ontario subsequently sought a ruling from its appeal court on the legality of connecting its online gambling system with players located outside the province. The province contended that shared liquidity would attract more gamblers to the regulated market. Several provincial lottery corporations opposed this view. In November, a majority decision at the lower court supported Ontario's position, leading the matter to be brought before the Supreme Court of Canada. If the Supreme Court upholds the lower court's ruling, poker and DFS players in Ontario could potentially be grouped with players from the United States or other countries. This could make paid DFS a viable option again in Ontario, although success is not guaranteed. Alberta sees a direct parallel with its own plans. Its July 13 market launch will adopt rules similar to Ontario's, including the requirement for gamblers to be physically within the province when placing bets. This could impose similar limitations on poker and DFS unless broader liquidity becomes feasible. Alberta has indicated that the Supreme Court case should not impede its market launch, but acknowledges that the outcome could influence the new market's functionality. In its submission, Alberta stated that its legislation does not prohibit individuals from outside Canada from participating in games operated by regulated provincial entities, provided that the authorities in those other countries permit it. The province argued: “Consequently, this appeal will have a significant impact on determining the legality and operation of the iGaming Alberta Act,” and added that “the views of AGAB should be considered by this Court.”The same filing outlined Alberta's desired legal interpretation. It argued that federal criminal law should be interpreted in a "flexible and broad manner so that it does not conflict with valid provincial legislation regulating gaming." Opposition Already Established This stance aligns Alberta closely with Ontario and places it in opposition to government lottery groups in Atlantic Canada, British Columbia, and Quebec. Quebec was approved as an appellant on April 2. These groups, often collectively referred to as the Canadian Lottery Coalition, have argued that allowing provinces to access international iGaming liquidity could lead to detrimental consequences and set a problematic precedent. Other approved interveners include the Canadian Gaming Association and Flutter Entertainment PLC, the owner of FanDuel. A hearing date has not yet been scheduled. FAQ What did Alberta achieve at the Supreme Court of Canada? Alberta successfully obtained leave to intervene in a gambling case, granting it the right to submit a 10-page factum and deliver a five-minute oral argument. Can Alberta fully argue its case? No. Alberta is restricted from advocating for a specific outcome, introducing new issues or evidence, or repeating arguments already presented by other parties. Why is this case important for Alberta? Alberta is set to launch a regulated iGaming market on July 13, and the court's decision could impact how the market handles poker, DFS, casino gaming, and sports betting. Which operators are expected to enter Alberta's new market? Prominent brands mentioned in the report include bet365, DraftKings, FanDuel, and Play Alberta. What initiated the legal dispute? Ontario's 2022 iGaming launch and its regulations concerning pay-to-play DFS and in-province wagering were key factors that led to the current legal challenge. What could be the consequence if the lower court's ruling is upheld? Players of poker and DFS in Ontario might be able to participate in games alongside players from the United States or other countries. This article is provided by a third-party. AsiaGameHub (https://asiagamehub.com/) makes no warranties regarding its content. AsiaGameHub delivers targeted distribution for iGaming, Casino, and eSports, connecting 3,000+ premium Asian media outlets and 80,000+ specialized influencers across ASEAN.
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DigiPlus Acquires Gaming Licences in South Africa’s Western Cape iGame

DigiPlus Acquires Gaming Licences in South Africa’s Western Cape

(AsiaGameHub) - DigiPlus has officially entered the South African market following the acquisition of online gaming licences in the Western Cape. This regulatory approval provides the Philippines-based firm with a gateway into one of Africa's most significant regulated online gaming sectors, aligning with its broader international growth strategy. Key Highlights The Western Cape Gambling and Racing Board has granted DigiPlus three online gaming licences. The firm identifies South Africa as Africa's premier online gaming market, projecting revenues of $4.9 billion for 2025. Following its entry into Brazil, South Africa marks the second international territory for DigiPlus. DigiPlus Opens South Africa Path With Western Cape Approval DigiPlus Interactive Corp has secured three licences from the Western Cape Gambling and Racing Board, establishing a foundation for its online gaming operations in South Africa. In a disclosure to the Philippine Stock Exchange on Thursday, the company confirmed that the approvals include a national manufacturer licence, a bookmaker licence, and a bookmaker premises licence. The company had previously indicated its intentions in late September, noting that it had submitted three online-related applications to the WCGRB. The Western Cape, home to the provincial capital of Cape Town, holds strategic importance beyond its borders. DigiPlus noted that the province represented approximately 31% of the nation's online gaming revenue in 2025, characterizing it as South Africa's largest online gaming market. The company further highlighted that the region is attractive to global operators due to its digital infrastructure and transparent regulatory framework. DigiPlus estimates the total South African gaming market to be worth $4.9 billion in 2025, making it a primary focus for the group's expansion beyond the Philippines. South Africa is positioned to be the company's second international market, following its venture into Brazil.The expansion into Brazil has faced challenges. After launching last year, DigiPlus suspended its gaming platform operations in mid-October, less than a month after the rollout. In its latest filing, the company stated its intention to resume full commercial operations in Brazil during the first half of 2026. Domestically, DigiPlus maintains a diverse digital gaming portfolio. The group manages BingoPlus, recognized as the first government-sanctioned online bingo platform in the Philippines, alongside the sports betting site ArenaPlus and the casual gaming platform GameZone. Additionally, a subsidiary operates various casino slot arcades throughout the country. The company is also pursuing a significant land-based investment. DigiPlus is currently acquiring $204.1 million (HKD1.60 billion) in convertible notes issued by International Entertainment Corp. This transaction would grant DigiPlus control over the New Coast Hotel Manila, a property currently undergoing redevelopment into an integrated resort in the Philippine capital. Recent financial performance has seen a decline. In March, DigiPlus reported that its fourth-quarter net income dropped 36% year-on-year to $41.9 million (PHP2.5 billion). Total revenue for the quarter ending December 31 reached $307.6 million (PHP17.3 billion), representing a 27% decrease compared to the same period in the previous year. This article is provided by a third-party. AsiaGameHub (https://asiagamehub.com/) makes no warranties regarding its content. AsiaGameHub delivers targeted distribution for iGaming, Casino, and eSports, connecting 3,000+ premium Asian media outlets and 80,000+ specialized influencers across ASEAN.
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3 Years and 11 Months! ‘AI+All-in-One PV Storage’ Sigenergy Listed on HKEX: Fastest IPO Record for a Chinese Enterprise ACN Newswire

3 Years and 11 Months! ‘AI+All-in-One PV Storage’ Sigenergy Listed on HKEX: Fastest IPO Record for a Chinese Enterprise

HONG KONG, Apr 16, 2026 - (ACN Newswire via SeaPRwire.com) - Sigenergy Technology Co., Ltd. (“Sigenergy” or “the company” Stock Code: 06656.HK) officially commenced trading on the Main Board of the Hong Kong Stock Exchange (HKEX) today. As the first “AI + All-in-One PV Storage” company to list on the exchange, Sigenergy has set a new record for the fastest IPO by a Chinese enterprise.The stock showed strong momentum on its debut, opening at HK$ 581, representing almost an 80% increase over the offer price. Market cap exceeded HK$140 billion. Based on the offer price of HK$324.20 per share, the company raised over HK$4.4 billion in its IPO. If the over-allotment option (greenshoe) is exercised in full, the total proceeds will reach HK$5.06 billion.A Milestone for the Company, the Beginning for a New ChapterFounded only 3 years and 11 months ago, Sigenergy’s rapid path to listing reflects its focus on defining new industry standards rather than following short-term market trends. The IPO attracted a prestigious group of cornerstone investors, highlighting the company’s strategic value in the 2026 Hong Kong market.At the listing ceremony, Mr. Xu Yingtong, Founder and CEO of Sigenergy, together with Mr. Zhang Xianmiao, President of Sigenergy, witnessed this pivotal milestone in the company’s journey.Mr. Xu Yingtong stated: “Listing marks a new beginning for us. Guided by our ‘AI in All’ mission, we are doubling down on energy storage and accelerating R&D to fortify our competitive edge. Our goal is to ensure that AI translates into tangible value for our customers. As we advance our global expansion and refine our international network, we are proud to share the story of ‘China’s Intelligent Manufacturing’ in the renewable energy sector. We promise to uphold the highest standards of operational excellence, rewarding your trust with exceptional results and building a legacy as a transparent, reliable, and socially responsible enterprise.” Sigenergy’s cornerstone investors include world-class sovereign wealth funds and asset managers such as Temasek, Goldman Sachs Asset Management, UBS Asset Management, and BNP Paribas Asset Management. Other notable participants include Hillhouse, CPE, Boyu Capital, Gaoyi Asset Management, and Greenwoods Asset Management, alongside insurance and specialized funds like CPIC, ORIX, and Walden International.This diverse group of high-caliber investors signals a strong market consensus: Sigenergy is recognized as a unique player in the “AI + All-in-One PV Storage” sector, underpinned by proprietary technology, high entry barriers, and predictable growth. Beyond a mere endorsement of the company, this capital influx confirms the market’s conviction that “AI-native” architecture is the definitive standard for next-generation energy storage.Market confidence is supported by Sigenergy’s rapid scale-up. According to the prospectus, the company’s revenue grew from RMB 58.30 million in 2023 to RMB 9.00 billion in 2025, increased 154.4 times in two years. During this period, gross margins expanded from 31.3% to 50.1%, with an adjusted net margin reaching 35.9%. These figures validate the commercial viability of Sigenergy’s “AI-native” technology path.Differentiation Through “AI-Native” TechnologyUnlike traditional “hardware-first, AI-enabled” peers, the company established a more thorough “AI-native” path by integrating artificial intelligence across product design, manufacturing, and business models, the company has achieved a system that is inherently intelligent and capable of continuous evolution.Its flagship product, SigenStor, is a five-in-one system that combines an inverter, EV DC charging module, and battery pack into a modular, stackable unit which achieves a deep integration of power electronics, cloud and AI technologies, enhances product performance while delivering a more convenient user experience.The actual value of system’s “AI-native” capabilities is particularly effective in markets with dynamic electricity pricing. Facing fluctuations on an hourly or even minute-by-minute basis, traditional “charge at low, use at high” strategies based on fixed rules are no longer sufficient. By analyzing real-time prices, weather forecasts, and consumer habits, the system optimizes energy scheduling. In the Swedish market, SigenStor helped users reduce electricity costs by an average of 70.3%, showing the effective translation from AI technology into tangible financial benefits.Sigenergy continuously strengthens its competitive edge through a “Data-Intelligence” closed-loop. As global install base grows, the system leverages real-world operational data to undergo autonomous learning and optimization. This evolution directly translates into superior economic returns for users, which in turn fosters brand loyalty and higher retention. This data-driven cycle creates a powerful network effect, establishing a formidable, long-term barrier to entry in the Energy AI sector.Since its launch, SigenStor has established a strong global presence through its unique value proposition. According to Frost & Sullivan, Sigenergy has become the world No.1 provider of stackable distributed PV and storage all-in-one solutions in 2024, securing a 28.6% market share. Further data from SunWiz confirms that in 2025, the company ranked first in the under-1000kWh segment across Australia, Ireland, and South Africa, while maintaining a top-tier position in the UK, Sweden, and the Netherlands. This deep penetration into high-value markets has delivered significant commercial returns and reinforced Sigenergy’s brand equity. As the company expands into the Asia-Pacific and Latin American regions, its growth trajectory remains robust.To support the trajectory, the company has built a robust manufacturing footprint with production bases in Lingang and Jinqiao, Shanghai, as well as Nantong, Jiangsu. By the end of 2025, the company achieved an annual design capacity of nearly 360,000 inverters and over 5.6 GWh of energy storage batteries. This infrastructure provides a stable foundation for the company’s ongoing global expansion.The successful HKEX listing marks a significant milestone in Sigenergy’s commitment to innovation and recognizes its substantial growth potential. Entering this new chapter, and with the support of premier institutional investors, Sigenergy will focus on optimizing resource integration and accelerating its global ‘AI + Energy Storage’ strategy. By solidifying its technological leadership and market presence, the company aims to build a sustainable foundation for long-term value creation.For inquiries, please contact:EVER BLOOM (HK) COMMUNICATIONS CONSULTANTS GROUP LIMITEDMs. Claire ZhangTel: (852)3468 8171Email: project_alps.list@everbloom.com.cn Copyright 2026 ACN Newswire via SeaPRwire.com. All rights reserved. www.acnnewswire.com
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3年11月!「AI+光儲一體化第一股」思格新能源刷新中國企業港股IPO最快紀錄 獲淡馬錫、高瓴等「全明星」資本加持 ACN Newswire

3年11月!「AI+光儲一體化第一股」思格新能源刷新中國企業港股IPO最快紀錄 獲淡馬錫、高瓴等「全明星」資本加持

香港, 2026年4月16日 - (亞太商訊 via SeaPRwire.com) - 4月16日,思格新能源(上海)股份有限公司(以下簡稱「思格新能源」,股票代碼:06656.HK)正式登陸港交所,在成為港股「AI+光儲一體化第一股」的同時,刷新了中國最年輕企業港股IPO最快紀錄,其超額認購近800倍亦創下2026年港股IPO最高認購紀錄,備受全球資本矚目。思格新能源上市首日強勢開盤,開盤價581港元,較發行價上漲80%,市值突破1400億港元。以324.20港元/股的發行價計,公司此次IPO募資規模超44億港元,若計入超額配售權(綠鞋)全額行使,募資總規模達50.6億港元。敲鑼上市,回響未來成立僅3年11個月,思格新能源即成功登陸港交所主板,不僅成為港股上市歷程最快、最年輕的中國企業,更匯聚全球頂級基石投資者,使其成為2026年港股市場基石實力最受矚目的IPO項目。在上市儀式上,思格新能源董事長、CEO許映童先生與公司總裁張先淼先生,共同見證思格新能源發展歷程中最重要的里程碑。許映童先生致辭稱:「上市是新的起點。我們將堅守『AI in All』戰略,深耕儲能領域,加大研發投入,強化技術壁壘,讓AI真正轉化為客戶價值。我們將繼續推進全球化,完善全球網絡,向世界講好中國智造的新能源故事。我們承諾,將以更穩健的經營、更優異的業績,回報每一份信任,努力成為一家讓投資者放心、讓社會認可的公眾公司。」思格新能源此次上市獲得了全球資本的鼎力支持,其基石投資者陣容堪稱「全明星」級別。其中既包括淡馬錫這類全球頂尖主權基金,也涵蓋高盛資產管理、瑞銀資產管理、法國巴黎銀行資產管理等國際一線資管機構,同時匯聚了高瓴、CPE源峰、博裕資本、高毅資產、景林資產等頭部投資機構,以及太平洋保險、富國基金等大型險資,更吸引了歐力士、霸菱、華登國際、蘭馨亞洲、3W Fund等專注不同領域的專業投資方。如此多元且頂級的資本齊聚,共同指向一個清晰共識,即思格新能源被一致視為「AI+新能源」賽道中兼具技術顛覆性、商業高壁壘與成長確定性的稀缺標的。這不僅是對思格新能源的認可,更是資本市場對「AI原生」作為下一代儲能核心形態的絕對信任。資本的青睞,最終需要市場表現來驗證。思格新能源同樣交出了令人滿意的答卷。招股書顯示,2023年至2025年,公司營收從5830.2萬元迅猛增長至90.01億元,兩年增幅高達154.4倍。更令人矚目的是其盈利能力的持續躍升,毛利率從2023年的31.3%大幅提升至2025年的50.1%,同期經調整淨利率達35.9%。思格新能源成功實現了規模與利潤的同步高速增長,印證了其「AI原生」技術路徑所構建的差異化競爭力與商業護城河。極致差異化AI+儲能:從技術重構到生態壁壘的全面領先思格新能源的戰略選擇,自公司創立之初就與行業絕大部分企業截然不同。當多數同行仍遵循「硬件先行,AI賦能」的漸進式疊加邏輯時,思格新能源則確立了一條更為徹底的「AI原生」道路,從產品設計、製造到商業模式,全面融入人工智能,實現系統的智能化和持續進化。公司核心產品SigenStor五合一光儲充一體機,將逆變器、直流充電模塊、儲能電池等多個核心部件高度集成,透過模塊化、可堆疊的設計,實現了電力電子、雲與AI技術的深度融合。不僅提升了產品性能,也為用戶帶來更便捷的使用體驗。在複雜動態電價市場中,SigenStor已驗證了「AI原生」系統的實際價值。面對電價小時級甚至分鐘級的波動,傳統基於固定規則的「低充高放」策略已力不從心。思格新能源的AI系統能夠綜合考慮實時電價、光伏預測和用戶用電習慣,實現智能化調度。在瑞典市場的應用中,該系統幫助用戶平均降低電費70.3%,真正實現了從簡單響應到多因素協同優化的跨越,讓AI技術轉化為用戶的實際收益。思格新能源透過「數據-智能」循環不斷強化自身優勢。隨著設備在全球的部署,系統可基於實際運行數據持續學習優化,提升智能水平。更高的智能水平帶來更優的經濟效益,進而增強用戶口碑與黏性,形成規模效應。這種由數據驅動的循環,正逐漸構建起思格在能源AI領域的長期壁壘。自推出市場以來,SigenStor就憑借獨特價值主張贏得全球認可。據弗若斯特沙利文報告,按產品出貨量計,思格新能源已成為全球排名第一的可堆疊分佈式光儲一體機解決方案提供商,2024年的市場份額高達28.6%。根據SunWiz報告,2025年思格新能源在澳大利亞、愛爾蘭、南非的1000kWh以下系統區間市場份額穩居第一,在英國、瑞典、荷蘭等市場也處於領先地位。在高價值市場的深度滲透,不僅帶來豐厚商業回報,更構築了堅實的品牌壁壘。隨著亞太、拉美等新興市場的拓展,公司增長空間持續擴大。為支撐業務快速發展,思格新能源已構建完善的產能佈局。公司目前在上海臨港、金橋及江蘇南通設有生產基地,截至2025年末,年設計產能達到近36萬台逆變器,儲能電池超5.6吉瓦時,為進一步全球化擴張提供堅實保障。成功登陸港股,是思格新能源以持續創新驅動發展、以高成長性獲得資本市場認可的重要里程碑。此次上市亦標誌著公司邁入全新發展階段。在資本市場支持與優質機構投資者的共同賦能下,思格新能源將進一步強化資源整合能力,加速推進「AI+儲能」戰略的全球化落地,持續鞏固在技術與市場端的領先優勢,穩固長期增長基礎,開拓更廣闊的發展空間。若有垂詢,請聯絡:九富(香港)財訊公關集團有限公司張緣/ Ms. Claire Zhang電話:(852)3468 8171電郵:project_alps.list@everbloom.com.cn Copyright 2026 亞太商訊 via SeaPRwire.com. All rights reserved. www.acnnewswire.com
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OBI Pharma 宣布將在 2026 年 AACR 年會上展示十篇海報,內容涵蓋 GlycOBI(R) 基於糖鏈的位點特異性抗體藥物偶聯物(ADC):單特異性與雙特異性(包括雙載荷)以及 Obrion(TM) ADC 賦能技術 ACN Newswire

OBI Pharma 宣布將在 2026 年 AACR 年會上展示十篇海報,內容涵蓋 GlycOBI(R) 基於糖鏈的位點特異性抗體藥物偶聯物(ADC):單特異性與雙特異性(包括雙載荷)以及 Obrion(TM) ADC 賦能技術

台北, 2026年4月16日 - (亞太商訊 via SeaPRwire.com) - OBI Pharma, Inc.(TPEx:4174.TWO)今日宣佈將出席 AACR 2026 年會,並透過十篇海報展示其 GlycOBI® 平台的變革性潛力。傳統 ADC 常因隨機偶聯而受到限制,導致藥物與抗體比值(DAR)不均一、穩定性不足以及治療窗口狹窄。相比之下,OBI 的位點特異性糖鏈技術可實現高度均一的 DAR,從而帶來更優的 PK/PD 特徵,並降低脫靶毒性,這一點已在 OBI 的主要項目 OBI-902 和 OBI-904 中得到驗證。我們正透過新一代雙特異性(OBI-201)以及雙特異性雙載荷(OBI-221)ADC 推動精準腫瘤學的進一步發展。這些“以生物學驅動”的分子旨在克服腫瘤異質性和多藥耐藥性——這是當前癌症治療中的關鍵挑戰。透過結合 GlycOBI® 與 GlycOBI DUO® 平台,OBI 正在開發具有創新性和差異化的療法,以滿足難治性實體瘤患者尚未被滿足的醫療需求。此外,OBI 強大的 ADC 偶聯平台已被證明能夠穩定實現產品品質與可擴展性,同時支援向下一代治療模式拓展,包括降解劑-抗體偶聯物(DAC)。這些數據將於 2026 年 4 月 17 日至 22 日在美國加利福尼亞州聖地亞哥舉行的美國癌症研究協會(AACR)年會上展示。“在 OBI,我們致力於打造更優質的 ADC,”OBI Pharma 首席科學官陳雅琪博士表示。“我們的目標是提供不僅能夠更有效、更精準靶向腫瘤,同時還能減少副作用的療法,為患者帶來具有潛在改變生命意義的治療選擇。”2026年4月20日(星期一)(上午9:00 - 12:00)標題:透過 OBI-902 克服耐藥性:下一代 TROP2 ADC 的臨床前評估1 作者:Ren-Yu Hsu, Chi-Huan Lu, Chi-Sheng Shia, Jing-Rong Huang, Hsin-Shan Wu, Lu-Tzu Chen, Jhih-Jie Yang, Tzu-Min Yen, Jyy-Shiuan Tu, Yu-Hsuan Tsao, Ya-Chi Chen。OBI Pharma, Inc,台灣台北 會議主題:PO. ET07.01 - 定量藥理學與轉化建模 地點:海報區 17 海報編號:6 摘要編號:1818標題:OBI-904,一種靶向 Nectin-4 的下一代 Exatecan ADC,展現出增強的細胞毒性並克服 Enfortumab Vedotin 耐藥性2作者:Yuan-Liang Wang, Chi-Huan Lu, Woan-Eng Chan, Shin-Jin Lin, Ting-Yu Chang, Hong-Syuan Lin, Wei-Jhen Huang, Ya-Chi Chen。OBI Pharma, Inc,台灣台北會議主題:PO.ET02.02 - 抗體藥物偶聯物與連接子工程 2 地點:海報區 13 海報編號:26 摘要編號:1729標題:OBI-904,一種基於糖鏈的位點特異性靶向 Nectin-4 的 ADC,在非臨床研究中展現出強效且持久的抗腫瘤活性,並具有改進的 PK 特徵及克服 EV 耐藥性的能力3 作者:Chi-Huan Lu, Ren-Yu Hsu, Jing-Jie Ciou, Tzu Min Yen, Jyy-Shiuan Tu, Yu-Hsuan Tsao, Jing-Rong Huang, Ya-Chi Chen。OBI Pharma, Inc., 台灣台北會議主題:PO.ET07.01 - 定量藥理學與轉化建模 地點:海報區 17 海報編號:7 摘要編號:1819標題:具有雙載荷的 MET/HER3 抗體藥物偶聯物:一種消除腫瘤逃逸機制的雙靶點策略5 作者:Yuan-Liang Wang, Chi-Huan Lu, Woan-Eng Chan, Ting-Yu Chang, Hong-Syuan Lin, Cheng-Yen Wei, Shin-Jin Lin, Lu-Tzu Lu, Meng-Hsin Liu, Wei-Jhen Huang, Ya-Chi Chen。OBI Pharma, Inc., 台灣台北會議主題: PO.CL.0705 - 靶向抗原療法與免疫 地點:海報區 49 海報編號:17 摘要編號:2665標題:引導-效應 bsADC:透過協同內吞作用提升載荷遞送效率6作者:Wei-Jhen Huang, Woan Eng Chan, Meng-Hsin Liu, Yueh Chin Wu, Ya-Chi Chen。OBI Pharma, Inc., 台灣台北會議主題: PO.ET02.02 - 抗體藥物偶聯物與連接子工程 2 地點:海報區 13 海報編號:27 摘要編號:1730標題:親水性增強的連接子技術實現位點特異性的降解劑-抗體偶聯物,具有改進的穩定性和增強的活性7 作者:Yu-Hung Chen, Wei-Chien Tang, Chi-Dian Lu, Hung-Yi Lin, Wei-Jhen Huang, Nan-Hsuan Wang, Ya-Chi Chen, Teng-Yi Huang。OBI Pharma, Inc., 台灣台北會議主題:PO.ET02.02 - 抗體藥物偶聯物與連接子工程 2 地點:海報區 13 海報編號:28 摘要編號:1731標題:基於細胞的載荷釋放揭示雙載荷 ADC 中設計、位點及細胞依賴的比例變化8 作者:Nan-Hsuan Wang, Wei-Han Lee, Evelyn He, Li Chuan Huang, Yu-Chao Huang, David Teng-Yi Huang, Ya-Chi Chen。OBI Pharma, Inc., 台灣台北會議主題: PO.CH01.06 - 抗體、抗體藥物偶聯物與核酸 地點:海報區 38 海報編號:5 摘要編號:23972026 年 4 月 20 日(星期一)(下午 2:00 - 5:00)標題:TROP2 上調及其與 HER2 的相互作用介導曲妥珠單抗耐藥性4 作者:Yuan-Liang Wang, Chi-Huan Lu, Cheng-Yen Wei, Jye-Yu Huang, Woan-Eng Chan, Lu-Tzu Chen, Ya-Chi Chen。OBI Pharma, Inc., 台灣台北會議主題:PO.ET03.06 - 藥物耐藥性 1:抗體與 ADC 地點:海報區 12 海報編號:18 摘要編號:29722026 年 4 月 21 日(星期二)(上午 9:00 - 12:00)標題:基於糖鏈的位點特異性 ADC 透過改進的載荷遞送和免疫激活實現持續的腫瘤控制9 作者:Liu Chih-Chun, Tsai Yi-Chien, Huang Jing-Rong, Lo Fei-Yun, Pei Yu, Hsu Ren-Yu, Tu Tzu-Hsuan, Chen Ya-Chi。OBI Pharma, Inc., 台灣台北會議主題: PO.IM02.04 - 癌症中的適應性免疫 地點:海報區 6 海報編號:2 摘要編號:4234標題:透過新一代位點特異性糖鏈偶聯與雙載荷靈活性推進 ADC 治療的發展10 作者:Wei-Chien Tang, Yu-Hung Chen, Chih-Kang Chang, Ting-Wei Liu, Hung-Yi Lin, Wei-Jhen Huang, Chi-Huan Lu, Ren-Yu Hsu, Nan-Hsuan Wang, Ya-Chi Chen, Teng-Yi Huang。OBI Pharma, Inc., 台灣台北會議主題: PO.ET02.03 - 抗體藥物偶聯物與連接子工程 3 地點:海報區 12 海報編號:1 摘要編號:4423電子海報將於 4 月 17 日太平洋時間中午 12:00 起在 AACR 虛擬會議平台上線供瀏覽,同時也將於 4 月 18 日起在 OBI Pharma 官網(www.obipharma.com)上線。1 AACR 2026 年年會摘要在線發布 https://www.abstractsonline.com/pp8/#!/21436/presentation/45832 AACR 2026 年年會摘要在線發布 https://www.abstractsonline.com/pp8/#!/21436/presentation/53853 AACR 2026 年年會摘要在線發布 https://www.abstractsonline.com/pp8/#!/21436/presentation/45884 AACR 2026 年年會摘要在線發布 https://www.abstractsonline.com/pp8/#!/21436/presentation/50305 AACR 2026 年年會摘要在線發布 https://www.abstractsonline.com/pp8/#!/21436/presentation/40516 AACR 2026 年年會摘要在線發布 https://www.abstractsonline.com/pp8/#!/21436/presentation/54007 AACR 2026 年年會摘要在線發布 https://www.abstractsonline.com/pp8/#!/21436/presentation/54018 AACR 2026 年年會摘要在線發布 https://www.abstractsonline.com/pp8/#!/21436/presentation/64749 AACR 2026 年年會摘要在線發布 https://www.abstractsonline.com/pp8/#!/21436/presentation/131110 AACR 2026 年年會摘要在線發布 https://www.abstractsonline.com/pp8/#!/21436/presentation/5403關於 OBI PharmaOBI Pharma 是一家處於臨床階段的全球腫瘤學公司,成立於 2002 年,總部位於台灣。公司與其子公司 OBI Pharma USA, Inc. 致力於開發創新癌症療法,為具有緊迫醫療需求的患者提供新的治療選擇。OBI 的研究重點是新型抗體藥物偶聯物(ADC)。透過其專有的下一代偶聯技術平台 Obrion™,OBI 建立了多樣化的 ADC 設計模式。該平台整合了專有的偶聯和連接子技術,包括 GlycOBI®、GlycOBI DUO®、EndoSymeOBI®、HYPrOBI®,以及新型不可逆半胱氨酸偶聯技術 ThiOBI®,以推進下一代 ADC 解決方案。OBI 已開發出一系列下一代 ADC 項目,包括單特異性 ADC,如處於 I 期臨床評估階段的 OBI-902(TROP2)和 OBI-904(Nectin-4);雙特異性單載荷 ADC OBI-201(HER2 × TROP2);以及雙特異性雙載荷 ADC OBI-221(cMET × HER3)。為拓展 HYPrOBI® 連接子技術的應用範圍,OBI 進一步開發了 ThiOBI® 技術,以實現不可逆的基於半胱氨酸的偶聯。除 ADC 項目外,OBI 的資產還包括 OBI-3424,這是一種類首創的小分子前藥,靶向 AKR1C3,可在醛酮還原酶 1C3 高表達的腫瘤中選擇性釋放強效 DNA 烷化劑。更多資訊請訪問 www.obipharma.com 。關於 OBI-902 和 OBI-992OBI-902 是一種靶向 TROP2 的抗體藥物偶聯物(ADC),攜帶強效拓撲異構酶 I 抑制劑載荷,以藥物-抗體比值(DAR)為 4 殺傷腫瘤細胞。TROP2 在多種實體瘤中高度表達,如乳腺癌、肺癌、膽道癌、膽管癌(膽管細胞癌)、卵巢癌、胃癌等多種癌症類型,因此成為理想的癌症治療靶點。OBI-902 是一種新型位點特異性糖鏈偶聯 ADC,採用 OBI 專有的 GlycOBI® 平台,具有更高的穩定性和更強的親水性。在多種腫瘤模型中(包括非小細胞肺癌、三陰性乳腺癌和胃癌),OBI-902 展現出顯著的抗腫瘤療效、改進的藥代動力學特徵以及良好的安全性。其 IND 已於 2025 年 4 月 30 日獲得美國食品藥品監督管理局(US FDA)批准,並分別於 2025 年 11 月 16 日和 12 月 5 日獲得膽管癌及胃癌(包括胃食管結合部癌)的孤兒藥資格認定。I/II 期臨床試驗(NCT07124117)正在進行中,I 期 a 部分預計於 2027 年上半年完成。OBI-992 是另一種靶向 TROP2 的抗體藥物偶聯物(ADC),透過基於半胱氨酸偶聯的親水性可酶切連接子,以藥物-抗體比值(DAR)為 4 攜帶強效拓撲異構酶 I 抑制劑載荷。OBI-992 在體循環中保持穩定,並將該細胞毒性載荷遞送至表達 TROP2 的腫瘤細胞,從而在避免脫靶毒性的同時實現腫瘤細胞殺傷。OBI-992 的 IND 申請已於 2024 年 1 月獲得美國 FDA 批准,並於 2024 年 8 月獲得用於治療胃癌(包括 GEJC)的孤兒藥資格認定。I/II 期研究(NCT06480240)已達到擬定的 II 期推薦劑量(pRP2D),I 期預計於 2027 年上半年完成。自 2021 年 12 月起,OBI 已獲得 Biosion, Inc.(www.biosion.com)授予的 TROP2 靶向抗體氨基酸序列在除中國大陸、香港和澳門以外所有地區的獨家許可。Biosion 在中國大陸、香港和澳門擁有該抗體序列的獨家權利。OBI 在除中國大陸、香港和澳門以外的所有地區擁有 OBI-992 和 OBI-902 的商業權利,而 Biosion 在中國大陸、香港和澳門擁有相應的商業權利。關於 OBI-904OBI-904 是一種抗體藥物偶聯物(ADC),由特異性靶向 Nectin-4(Nectin 細胞黏附分子 4)的單克隆抗體構成,透過 OBI 專有的 GlycOBI® ADC 賦能技術,並在雙功能酶 EndoSymeOBI® 和新型連接子 HYPrOBI® 的支援下,以藥物-抗體比值(DAR)為 8 偶聯強效拓撲異構酶 I 抑制劑載荷。該藥物有望成為同類首創及同類最佳的基於糖鏈的 ADC,旨在靶向多種表達 Nectin-4 的癌症類型。在多種動物疾病模型中(包括頭頸鱗癌、結直腸癌、三陰性乳腺癌、宮頸癌及肉瘤),其已顯示出抗腫瘤活性;在猴重複給藥毒性研究中,OBI-904 展現出良好的安全性,目前處於 IND 申請前開發階段。關於 OBI-201OBI-201 是一種 TROP2 × HER2 雙特異性 ADC,基於 OBI 的 GlycOBI® ADC 賦能技術構建,並偶聯拓撲異構酶 I 抑制劑。值得注意的是,OBI 首次證明 HER2 與 TROP2 可在細胞表面相互作用並形成蛋白複合物——這一突破性發現得益於與專業 AI 藥物研發合作夥伴的協作。與單特異性 TROP2 或 HER2 ADC 相比,OBI-201 具有多項優勢。透過同時靶向兩種抗原,它可擴大腫瘤覆蓋範圍,尤其適用於靶點表達異質性或表達水平較低的癌症。雙靶向可增強腫瘤選擇性、結合親和力及內吞作用,從而提高載荷向癌細胞的遞送效率,同時有望降低對正常細胞的毒性。OBI-201 還可能克服部分單特異性 ADC 治療後因靶點下調所產生的耐藥性。動物研究表明,在 HER2 表達極低的耐藥性乳腺癌模型中,OBI-201 相較於單靶點 ADC 展現出顯著更優的抗腫瘤活性。OBI-201 能夠持續抑制腫瘤生長,顯示出其克服多種耐藥機制的潛力。OBI-201 是一種新一代雙特異性 ADC,有望突破單靶點 ADC 的局限,為患者提供更全面且持久的治療選擇。關於 OBI-221OBI-221 是一種雙特異性雙載荷 ADC(BsDpADC),基於 OBI 的 GlycOBI DUO® 技術構建,靶向 cMET 和 HER3,並偶聯 MMAE 與拓撲異構酶 I 抑制劑雙載荷。在臨床實踐中,靶向 EGFR 的療法已成為治療非小細胞肺癌(NSCLC)和結直腸癌(CRC)的關鍵策略。然而,腫瘤常透過上調 cMET 和 HER3 快速產生耐藥性,從而維持腫瘤生長。此外,在胃癌、頭頸癌及多種其他實體瘤中也觀察到 cMET 和 HER3 的高表達,進一步凸顯了未被滿足的醫療需求。為應對這一挑戰,OBI Pharma 利用其專有的 GlycOBI DUO® 平台和 HYPrOBI® 連接子開發了新型雙特異性雙載荷抗體藥物偶聯物(BsDpADC)——OBI-221。該治療藥物可同時靶向 cMET 和 HER3,並遞送具有協同作用的細胞毒性載荷,從而有效對抗腫瘤耐藥性和異質性。這一突破性設計不僅滿足未被滿足的醫療需求,也代表了下一代 ADC 開發的前瞻性策略。OBI-221 在克服現有 EGFR 靶向療法耐藥性方面具有重要潛力,有望為患者提供更具針對性的治療選擇,並帶來顯著的臨床價值。關於 GlycOBI®OBI 開發了一種獨特的基於糖鏈的位點特異性 ADC 技術(GlycOBI®),採用即插即用(Plug and Play)設計,可兼容任意抗體、連接子和載荷,並支援多種藥物-抗體比值(DAR)(最高可達 16)。該技術由 OBI 專有的雙功能酶技術 EndoSymeOBI® 和親水性連接子技術 HYPrOBI® 驅動,作為 OBI Obrion™ ADC 技術體系的核心組成部分,能夠在 GMP 條件下透過高效、可規模化、流程簡化的兩步一鍋法偶聯工藝生成位點特異性且高度均一的 ADC。在偶聯過程中,GlycOBI® 避免破壞抗體結構,並確保生成的 ADC 保持與天然抗體相當的生物物理特性。此外,OBI 的連接子技術提高了載荷偶聯效率,並降低了聚集或降解的傾向,從而進一步支援穩定且可控的 ADC 生產過程。GlycOBI® 克服了傳統 ADC 方法常見的局限,並在多項體內研究中展現出更優的抗腫瘤活性和穩定性。值得注意的是,該平台支援偶聯細胞毒性小分子抑制劑以及高度疏水性的降解劑,從而拓展至包括 DAC 在內的下一代治療模式。關於 GlycOBI DUO®GlycOBI DUO® 是一種基於 GlycOBI® 位點特異性偶聯平台及其專有酶促偶聯策略構建的下一代雙載荷抗體藥物偶聯物(ADC)技術。該技術可在單一抗體上以可調比例精確、可編程地連接兩種不同載荷,並支援高 DAR 比值(最高可達 DAR24)。透過結合互補的作用機制,GlycOBI DUO® 旨在增強抗腫瘤療效、應對腫瘤異質性並提升整體治療指數,同時具備克服傳統 ADC 相關耐藥機制的潛力,代表了下一代 ADC 開發的重要進展。關於 ThiOBI®OBI 開發了一種新型不可逆半胱氨酸偶聯 ADC 平台(ThiOBI®),具有更高的穩定性,可適用於任意抗體、連接子和載荷。OBI 專有的 ThiOBI® 平台結合連接子技術(HYPrOBI®),可生成多種生物分子形式的 ADC,包括抗體片段、納米抗體、肽類和蛋白質。此外,OBI 的 HYPrOBI® 連接子技術提高了載荷的偶聯效率,降低了聚集傾向,並延長了 ADC 產品的半衰期。ThiOBI 克服了傳統半胱氨酸 ADC 的局限,並在多項體內研究中實現了更優的抗腫瘤活性和穩定性。GlycOBI®、EndoSymeOBI®、ThiOBI®、HYPrOBI® 和 GlycOBI DUO® 為 OBI 的註冊商標。Obrion™ 為正在申請註冊的商標。前瞻性聲明本新聞稿中非歷史事實的陳述屬於《1995 年私人證券訴訟改革法》所定義的前瞻性聲明。此類前瞻性聲明包括但不限於關於未來臨床試驗、試驗結果及其時間安排的陳述。相關風險因素已在 OBI Pharma 的報告和演示材料中不時披露,包括其向台灣證券期貨局提交的文件。公司聯絡人:Jukka MuhonenExecutive Director, Business DevelopmentOBI Pharma USA, Inc.1.617.821.0292 jukkamuhonen@obipharma.com來源: OBI Pharma USA, Inc. 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教師,請先自省:Yale報告痛批常春藤盟校摧毀美國對高等教育的信任 News

教師,請先自省:Yale報告痛批常春藤盟校摧毀美國對高等教育的信任

(SeaPRwire) - 美國的學院和大學正面臨正當性危機,而耶魯大學(Yale University)剛發布了一份最坦率的機構診斷報告之一,探討它們如何走到這一步,以及需要採取什麼措施才能擺脫困境。 由耶魯大學校長Maurie McInnis召集的教職員委員會在周三發布了一份全面報告,探討公眾對高等教育信心的崩潰,並對該領域在成本、招生、言論自由和治理方面的失敗進行了直言不諱的評估。這項為期一年的研究結果,是精英大學公開進行的最具自我批判精神的調查之一。該報告發布之際,耶魯及其常春藤盟校(Ivy League)的同行正面臨來自多方面的壓力——不僅是持懷疑態度的公眾,還有將資金作為對抗校園自治的直接手段的聯邦政府。 「我們認為信任下降的問題是真實且緊迫的,必須加以解決,」委員會在給McInnis的開場信中寫道。 數據支持了他們的觀點。就在十年前,57%的美國人表示他們對高等教育有很大或相當大的信心。根據報告中引用的蓋洛普(Gallup)和皮尤(Pew)的調查,到2024年,這一數字已降至歷史最低點36%。儘管2025年信任度略有上升,但70%的美國人仍然認為高等教育「正朝著錯誤的方向前進」。而學術界中沒有哪個領域比常春藤盟校更受質疑——這些機構長期以來一直將自己定位為黃金標準。 報告指出信任崩潰背後的三個主要原因: 失控的成本 不透明且不公平的招生制度 越來越敵視言論自由的校園氛圍 委員會謹慎地指出,問題的根源比任何單一問題都更深層次。報告指出:「近年來,人們期望大學能滿足所有人的所有需求——既精選又包容,既負擔得起又奢華,既講究精英主義又公平。」「這種目標的分散非但沒有建立公眾支持,反而助長了不信任。」換句話說,你無法取悅所有人,反而可能讓所有人都不開心。 飛漲的學費成本 在成本方面,委員會毫不留情。耶魯大學今年的總就學成本為94,425美元,而該國的家庭中位收入低於84,000美元。在一項全國民意調查中,86%的受訪者認為耶魯「太貴」。委員會承認,該大學的高學費、高補助模式——大約五分之一的本科生可全額獎學金就讀——已悄悄提高了耶魯的可及性,但認為該制度「複雜、難以預測、祕密且變化極大」。結果是:近一半的美國人甚至不相信存在如此規模的財務援助。 耶魯在1月份採取行動彌合這種認知差距,宣布將免除年收入低於20萬美元家庭的學費,並為年收入低於10萬美元的家庭支付全部就學成本——這項政策將於2026年秋季對入學新生生效。該大學表示,根據新規則,超過80%的美國家庭將有資格獲得至少部分獎學金資助。然而,委員會的報告發現,溝通失誤與政策失誤同樣具有破壞性——耶魯必須做更多工作,讓公眾了解其負擔能力的情況。 招生過程受到質疑 招生章節可能引發最多爭議。耶魯2030屆的錄取率為4.2%,委員會質疑長期以來被視為組建多元化、有才華班級工具的整體評估過程是否真正兌現了承諾。報告引用經濟學家Raj Chetty、David Deming和John Friedman的研究指出,來自收入分配前1%的申請者比同等資歷的中產階級同齡人更有可能獲得錄取。校友子女優待政策(legacy preferences)和招募運動員是造成這種差距的主要原因。儘管如此,自這些研究結果發布以來,精英大學已有兩年多的時間採取行動;耶魯委員會的報告表明,大部分時間窗口被浪費了。 校園自我審查 言論自由和自我審查同樣受到嚴厲審視。2025年耶魯的一項調查發現,近三分之一的本科生在校园裡不敢自由表達自己的政治觀點——高於2015年的17%。委員會還指出了一個令人擔憂的新趨勢:博士後研究員和國際學生報告說,即使是關於自己的研究,他們也因害怕政府報復而猶豫不決。 這種恐懼有記錄在案的現實依據。過去一年,特朗普政府在哈佛大學(Harvard)拒絕遵守白宮限制校園行動主義的要求後,凍結了給哈佛的22億美元聯邦撥款,後來威脅要削減所有聯邦資金,並成立了一個任務組調查哈佛總計87億美元的合同和撥款。這種寒蟬效應已蔓延至常春藤盟校,多所機構的博士後和國際研究人員報告稱,他們對公開發表自己的研究感到越來越焦慮。 委員會發布了20項建議,涵蓋招生改革、提高預算透明度、遏制行政膨脹,以及重新承諾耶魯1974年《伍德沃德報告》(Woodward Report)中關於言論自由的原則。它敦促該大學超越表面功夫。報告指出:「建立信任需要持續關注公眾對高等教育體系的需求和期望。」 委員會一致提交了調查結果——這也許是一個信號,表明精英學術界終於願意大聲說出公眾長期以來所相信的事情。 在這篇報導中,記者使用生成式AI作為研究工具。編輯在發布前驗證了信息的準確性。本文由第三方廠商內容提供者提供。SeaPRwire (https://www.seaprwire.com/)對此不作任何保證或陳述。 分類: 頭條新聞,日常新聞 SeaPRwire為公司和機構提供全球新聞稿發佈,覆蓋超過6,500個媒體庫、86,000名編輯和記者,以及350萬以上終端桌面和手機App。SeaPRwire支持英、日、德、韓、法、俄、印尼、馬來、越南、中文等多種語言新聞稿發佈。
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貝佐斯與馬斯克的太空競爭正瞄準月球,勝出者不僅將主宰宇宙,更將主導AI基礎設施的未來 News

貝佐斯與馬斯克的太空競爭正瞄準月球,勝出者不僅將主宰宇宙,更將主導AI基礎設施的未來

(SeaPRwire) - 伊隆·馬斯克(Elon Musk)與傑夫·貝佐斯(Jeff Bezos)是全球三大富豪中的兩位,他們正展開一場爭奪太空主導權的高空對決,其結果可能決定月球旅行乃至人工智慧(AI)基礎設施的未來。 本月早些時候,阿爾忒彌斯二號(Artemis II)任務成功完成,這是50年來宇航員首次飛越月球。鑒於此,馬斯克的SpaceX和貝佐斯的Blue Origin都將注意力從其他專案轉移到未來月球任務的準備上。多年前,這兩家公司都獲得NASA數十億美元的合約,為未來兩次阿爾忒彌斯任務開發月球著陸器,這些任務計畫在本世紀末前讓人類自1972年以來首次登上月球。 伊隆·馬斯克的SpaceX對決傑夫·貝佐斯的Blue Origin SpaceX正在開發其「人類著陸系統」(Human Landing System),這是一款雄心勃勃的著陸器,高達165英尺(約15層樓高),比以往任何著陸器都要大,並將使用電梯從著陸器頂部附近的乘員艙將宇航員和貨物運送到月球表面。 與此同時,Blue Origin正在開發其「藍月亮」(Blue Moon)著陸器。儘管它看起來更像傳統著陸器,但技術也很先進。據Space.com報導,它將配備光達(lidar)感測器,用於繪製月球表面地圖,以規避危險並找到最平坦的著陸區域。這兩家公司的著陸器都設計為可重複使用,旨在降低未來月球任務的成本。 SpaceX和Blue Origin的風險很高。無論哪款月球著陸器先準備就緒並成功測試,最終都將幫助美國在2030年(中國計畫登陸月球的時間)之前讓宇航員登上月球,從而擊敗中國。 首次測試將是阿爾忒彌斯三號(Artemis III)任務,計畫於2027年中期進行,該任務可能會測試SpaceX和Blue Origin的著陸器——如果它們能按時準備就緒的話。作為任務的一部分,宇航員將乘坐搭載NASA奧利安太空艙(Orion capsule)的火箭進入近地軌道,類似於阿爾忒彌斯二號任務使用的太空艙。如果一切按計畫進行,SpaceX和Blue Origin將分別發射其著陸器進入太空,測試它們與奧利安飛船的對接能力。這將是2028年阿爾忒彌斯月球登陸關鍵過程的首次測試。在月球登陸期間,奧利安太空艙和月球著陸器將分開發射,並在月球軌道對接,然後宇航員降落到月球表面。 這次首次競爭也將使NASA更接近在這個天體上建立永久存在。NASA上月宣布了一項分階段計畫,旨在建造永久月球基地,並概述了在2028年首次月球登陸後,每六個月進行一次載人表面登陸,以建立月球基地基礎設施的策略。根據NASA的一份演示文稿,這些努力是NASA推動在月球南極建立人類存在的一部分,這「將加強美國在太空的領導地位,帶來科學發現,並成為載人火星任務的試驗場」。 儘管馬斯克的SpaceX成立於2002年,比Blue Origin晚兩年,但該公司在許多方面都領先競爭對手好幾光年。它是第一家開發出商業驗證可重複使用火箭「獵鷹9號」(Falcon 9)的公司,自2010年首次成功任務以來,該火箭已成為行業的指路明燈。據Space.com報導,SpaceX去年使用獵鷹9號進行了165次發射,打破了前一年的發射紀錄,同時占據了美國所有軌道發射的85%。它還使用獵鷹9號組建了有史以來最大的衛星艦隊,軌道上有10,000顆衛星,為其Starlink衛星互聯網服務提供動力。 儘管取得了這些成就,貝佐斯仍押注Blue Origin將通過緩慢而穩定的步伐取勝。 該公司在2025年使用其New Glenn火箭完成了首次軌道發射,並成功進入軌道,儘管其助推器並未按計畫回收再利用。去年11月,該公司在協助發射兩個火星探測器(作為NASA的「逃脫與等離子體加速動力探測器」(Escapade)任務的一部分)後,成功將其助推器降落在地球上。 太空中的AI基礎設施 隨著AI在地球上不斷加速發展,Blue Origin和SpaceX都在探索將支撐AI的基礎設施移至太空的想法。SpaceX資深人士、Portal Space Systems首席執行官傑夫·索恩伯格(Jeff Thornburg)此前表示,儘管這一想法仍處於早期階段,但隨著未來更強大的太陽能陣列的出現,太空數據中心將具有利用更清潔太陽能的優勢。在遠離地球的高空,這些未來的浮動數據中心也將擺脫公司在地球上建造基礎設施時面臨的法規限制和無數抗議。 儘管如此,將AI數據中心置於太空是否可行仍不明確。技術和財務挑戰令人驚訝,尤其是將硬體發射到軌道的成本遠高於在地球上建造AI基礎設施。然而,SpaceX和Blue Origin都已採取行動進行準備,以防萬一。 SpaceX已向聯邦通信委員會(Federal Communications Commission)提交計畫,計畫發射多達100萬顆具備AI計算能力的衛星進入太空。Blue Origin則在上月向FCC申請許可,發射近52,000顆具備AI計算能力的衛星進入太空。 「軌道數據中心是滿足AI計算能力不斷增長需求的最有效方式,」SpaceX在其申請文件中寫道。 正如貝佐斯去年在義大利都靈的一場科技會議上預測的那樣,在未來幾十年裡,AI的下一個前沿可能是地球之外。 「太空最終將成為不斷改善地球的地方之一。氣象衛星已經做到了這一點,通信衛星也已經做到了這一點,」他說。「下一步將是數據中心和其他類型的製造業。」本文由第三方廠商內容提供者提供。SeaPRwire (https://www.seaprwire.com/)對此不作任何保證或陳述。 分類: 頭條新聞,日常新聞 SeaPRwire為公司和機構提供全球新聞稿發佈,覆蓋超過6,500個媒體庫、86,000名編輯和記者,以及350萬以上終端桌面和手機App。SeaPRwire支持英、日、德、韓、法、俄、印尼、馬來、越南、中文等多種語言新聞稿發佈。
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Amusnet expands into Czech market via partnership with Paradise Casino Admiral iGame

Amusnet expands into Czech market via partnership with Paradise Casino Admiral

(AsiaGameHub) - Amusnet has expanded its footprint in the Czech Republic by entering a new strategic alliance with Paradise Casino Admiral. Through this partnership, Paradise Casino Admiral has approved 122 Amusnet games and will initially introduce a curated set of 92. The selection encompasses popular titles like Shining Crown and Dice & Roll, alongside newer additions such as Cocktail Rush – Easter Edition. Jaroslav Staníček, Operations Manager at Paradise Casino Admiral, stated: “This collaboration with Amusnet enables us to provide our players with a broad selection of innovative, high-quality games that match current market trends. We are excited to diversify our game library and offer fresh experiences to our clientele.” This new deal represents Amusnet's second partnership in the Czech market, following its initial entry with Tipsport in May 2024. Amusnet has characterized the agreement as a significant move in its European expansion strategy, coming after the recent launch of its Jackpot Cards Plus island in Georgia with Casino Adjara in March. Michal Burgert, Account and Commercial Manager at Amusnet, remarked: “We are thrilled to provide our comprehensive game portfolio to a top-tier operator like Paradise Casino Admiral. Featuring a powerful blend of timeless classics and compelling new games, we believe this launch will achieve excellent outcomes and appeal strongly to Czech players.” A decade of iGaming evolution Amusnet is nearing its ten-year anniversary, and earlier this year, the company's Chief Technology Officer, Lazar Agatonovic, reflected on Amusnet's progress in an interview with iGaming Expert. “In the last ten years, Amusnet has transformed from a specialized content creator into a worldwide iGaming technology partner active in many regulated jurisdictions. Our foundational strategy was always to develop our own scalable technology to support lasting growth in a fiercely competitive industry governed by strict compliance,” he explained. Agatonovic further noted that Amusnet's current development priorities are centered on growing its organized game series, jackpot networks, promotional tools, and live casino and land-based segments. This article is provided by a third-party. AsiaGameHub (https://asiagamehub.com/) makes no warranties regarding its content. AsiaGameHub delivers targeted distribution for iGaming, Casino, and eSports, connecting 3,000+ premium Asian media outlets and 80,000+ specialized influencers across ASEAN.
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